Watch Closely (one)lenacapavir will raise the level or effect of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism.etravirine will reduce the level or effect of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Coadministration of fentanyl with CYP3A4 inducers could lead to your… Read More